Chromtech Evolution GC-MS/MS

GC-MS/MS Triple Quad

The Chromtech Evolution is built upon the most popular GC/MS-System, the Agilent 5973/5975 series MSD. Keeping the original inert ion source, the true hyperbolic quadrupole and the highly sensitive HED detector provides the best possible basis for the next logical step in mass spectrometry: MS-MS. By adding a proprietary IonRail collision cell and another high precision quadrupole–serving as mass filter Q3 – the Agilent MSD is easily upgraded to a triple quadrupole instrument, the Chromtech Evolution Imagine all the possibilities of MS/MS combined with the ruggedness and reliability of the Agilent MSD 5973/75 series base instrument.

Function and Advantages of Triple Quadrupole-MS/MS

A triple quadrupole mass spectrometer (QqQ) links two stages of mass analysis. The first quadrupole mass filter (Q1) pre-selects a precursor ion ("parent ion") which is fragmented by collision with an inert gas in the RF-only collision cell (q2). The resulting product ions ("daughter ion") are subsequently selected by the third quadrupole (Q3) mass filter. Using Multiple Reaction Monitoring (MRM) is the most sensitive and selective technique to quantitate low levels of target compounds, especially in the presence of high background from sample matrix. Chemical background, usually present in single quad analysis (SIM) is almost completely eliminated. Typical applications for the MS/MS technique are doping analysis, forensic science, drug testing, pesticide residues in food, biomarker analysis for oil exploration, dioxine trace analysis, etc. In essence, samples with heavy matrix.

Extracted ion (m/z 272) from full scan (m/z 90-300) of 1pg Octafluoronaphthalene (OFN)

SRM (m/z 272 > 222) of 1pg OFN

Daughterspectrum of 1pg OFN

Chromsys Evolution GC-MS/MS Data Sheet (775 kB pdf)

Chromsys Evolution GC-MS/MS (Low Res Web Only) Brochure(1.39MB pdf)